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技術名稱 Technology
發明人 Inventor
王靖維, 柯馨雅,
所有權人 Asignee 國立臺灣科技大學

專利國家 Country 申請號 Application No. 專利號 Patent No. 中心案號 Serial No.
中華民國 107121575 I684994 1070025TW0
中國 201811119907.4 申請中 1070025CN0
  點閱數:508

技術摘要:
Automatic alignment of 3D CT and MRI datasets with the highly deformable and flexible spine regions is challenging but critical for image-guided surgery systems. The proposed system presents a fully automatic 4D registration and fusion system, including a L-SVM vertebra detection, a vertebra localization method, a corresponding landmark detection approach and an elastic 4D registration approach. This method can help to register accurately 3D spine images from CT and MR even they are not taken at the same time or even their anatomical structure is different. In evaluation, a preliminary test conducted to compare nine registration methods with the presented registration approaches, and the top two benchmark methods with high registration accuracies and computing speed selected for full evaluation. In full evaluation, three proposed registration methods were compared with the selected top two benchmark methods using 78 pairs of 3D CT and MRI datasets from two group where each group has 39 pairs. For quantitative evaluation, corresponding landmarks on the CT and transformed MRI datasets are identified by human first and then the distances between the landmark positions are measured as registration errors. The results show that the proposed method is significantly better than the benchmark methods (p ≤ 0.001) in both groups. For the first group, the proposed method obtains the lowest error 12.3624 pixels (4.185mm) on average. In comparison, benchmark methods obtain notably larger mean error distances (41.8085 pixels (14.153mm) and 50.8003 pixels (17.1971mm)).

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